Table 1 Drug resistant rates of different MAC species
From: In vitro assessment of 17 antimicrobial agents against clinical Mycobacterium avium complex isolates
Antimicrobial agent | No. of resistant isolates (%) | P value | |||||||
|---|---|---|---|---|---|---|---|---|---|
All isolates n = 111 | M. intracellulare n = 81 | M. avium n = 13 | M. marseillense n = 7 | M. colombiense n = 7 | M. yongonense n = 1 | HZ347 n = 1 | 18-T1838 n = 1 | ||
CLA | 5(4.5%) | 3(3.7%) | 2(15.4%) | 0(0%) | 0(0%) | 0 | 0 | 0 | 0.139 |
RFB | 24(21.6%) | 17(21.0%) | 2(15.4%) | 1(14.3%) | 3(42.9%) | 0 | 1 | 0 |  > 0.999 |
EMB | 60(54.1%) | 33(40.7%) | 12(92.3%) | 6(85.7%) | 7(100%) | 1 | 1 | 0 |  < 0.001 |
INH | 111(100%) | 81(100%) | 13(100%) | 7(100%) | 7(100%) | 1 | 1 | 1 |  > 0.999 |
MXF | 67(60.4%) | 43(53.1%) | 8(61.5%) | 6(85.7%) | 7(100%) | 1 | 1 | 1 | 0.570 |
RIF | 92(82.9%) | 64(79.0%) | 11(84.6%) | 7(100%) | 7(100%) | 1 | 1 | 1 |  > 0.999 |
SXT | 69(62.2%) | 45(55.6%) | 10(76.9%) | 6(85.7%) | 5(71.4%) | 1 | 1 | 1 | 0.226 |
AMI | 3(2.7%) | 1(1.2%) | 2(15.4%) | 0(0%) | 0(0%) | 0 | 0 | 0 | 0.049 |
LZD | 80(72.1%) | 53(65.4%) | 11(84.6%) | 7(100%) | 6(85.7%) | 1 | 1 | 1 | 0.213 |
CIP | 97(87.4%) | 70(86.4%) | 10(76.9%) | 7(100%) | 7(100%) | 1 | 1 | 1 | 0.404 |
STR | 19(17.1%) | 17(21.0%) | 2(15.4%) | 0(0%) | 0(0%) | 0 | 0 | 0 |  > 0.999 |
DOX | 109(98.2%) | 79(97.5%) | 13(100%) | 7(100%) | 7(100%) | 1 | 1 | 1 |  > 0.999 |
ETH | 102(91.9%) | 75(92.6%) | 10(76.9%) | 7(100%) | 7(100%) | 1 | 1 | 1 | 0.107 |
TZD | 29(26.1%) | 24(29.6%) | 4(30.8%) | 0(0%) | 1(14.3%) | 0 | 0 | 0 |  > 0.999 |
CFZ | 22(19.8%) | 14(17.3%) | 4(30.8%) | 2(28.6%) | 2(28.6%) | 0 | 0 | 0 | 0.265 |
BDQ | 0(0%) | 0(0%) | 0(0%) | 0(0%) | 0(0%) | 0 | 0 | 0 |  > 0.999 |
CS | 34(30.6%) | 21(25.9%) | 9(69.2%) | 1(14.3%) | 2(28.6%) | 1 | 0 | 0 | 0.004 |