Table 2 Antimicrobial resistance genes are present in the pEC1390-1 and pEC1390-2
Plasmid | Antimicrobial resistance genes | Position in plasmid | Identity | Characteristics |
|---|---|---|---|---|
pEC1390-1 | dfrA17 | 4344.4812 | 98.95 | trimethoprim-resistant dihydrofolate reductase |
aadA5 | 4942.5728 | 99.75 | AadA family aminoglycoside 3″-O-nucleotidyltransferase | |
sul1 | 6273.7110 | 99.76 | sulfonamide-resistant dihydropteroate synthase | |
blea | 11,043.11381 | - | bleomycin binding protein Ble-MBL | |
blaNDM-5 | 11,408.12218 | 99.75 | NDM family subclass B1 metallo-β-lactamase | |
mph(A) | 13,597.14497 | 99.78 | Mph(A) family macrolide 2’-phosphotransferase | |
mrx(A)a | 14,506.15734 | - | macrolide resistance MFS transporter Mrx(A) | |
blaCTX-M-15 | 20,707.21579 | 99.66 | CTX-M family class A extended-spectrum β-lactamase | |
catB3 | 22,940.23378 | 99.10 | CatB-related O-acetyltransferase | |
blaOXA-1 | 23,512.24338 | 99.52 | OXA-1 family class D β-lactamase | |
aac(6')-Ib-cr | 24,467.24985 | 99.61 | fluoroquinolone-acetylating aminoglycoside 6’-N-acetyltransferase AAC(6')-Ib-cr5 | |
tet(A) | 28,507..29704 | 99.67 | tetracycline efflux MFS transporter Tet(A) | |
K7G95_00640a | 29,736.30619 | - | EamA family transporter | |
catA1 | 154,061.154715 | 99.10 | chloramphenicol acetyltransferase | |
pEC1390-2 | blaTEM-1B | 60,372..61228 | 95.54 | TEM family class A β-lactamase |
rmtB | 61,397.62139 | 98.28 | amikacin, gentamicin, tobramycin, kanamycin resistance |