Fig. 7

Anti-inflammatory activity of Tetragenococcus halophilus EFEL7002 in LPS-induced RAW 264.7 cells. Effect of heat-killed cells and lysates of T. halophilus EFEL7002 on (a) nitric oxide production (a), (b) mRNA expression of COX-2, and (c) mRNA expression of iNOS. Different letters on the error bars indicate significant differences (p < 0.05) according to Duncan’s multiple range test. In addition, significant differences with the LPS positive group are represented using asterisks (***p < 0.001). Abbreviations: LGG, Lacticaseibacillus rhamnosus GG; LPS, lipopolysaccharide; MA, methyl arginine; NO, nitric oxide; WCFS1, Limosilactobacillus plantarum WCFS1