Table 4 Results from 10 PCR-positive clinical specimens with suspected endocarditis
Material | Clinical information | PCR | Culture | Antibioticsb | Microscopy | Cp and copy number |
|---|---|---|---|---|---|---|
Valve replacement with vegetations | acute “prosthetic valve endocarditis” after dentist | Cutibacterium acnes | negative (blood culture not available) | Augmentin, rimactan, zyvoxid | negative | Cp 30.44 3 copies 16S rDNA |
Aortic valve | severe aortic regurgitation with thrombus situation after embolization duration of illness: 4 months | Cardiobacterium hominis | negative (blood culture not available) | none | negative | Cp 24.79 3 copies 16SrDNA |
Aortic valve | endocarditis with S.mutans | Streptococcus mutans | negative (blood cultures with S.mutans 18 days ago) | Penicillin G, gentamycin | negative | Cp 22.94 5 copies 16S rDNA |
Aortic valve | both valves involved mitral valve: PCR negative | Staphylococus coagulase negative | negative (blood culture not available) | Floxapen (since 2 days) | negative | Cp 26.70 ~ 6 copies 16S rDNA |
Aortic valve | endocarditis aortic and mitral valve | Staphylococcus epidermidis | S. epidermidis (only in enrichment culture) (blood cultures with S.epidermidis 2 and 3 days ago) | Vanco, tazobac | not done | Cp 24.57 6 copies 16S rDNA |
Mitral valve | endocarditis mitral valve with E.faecalis | Enterococcus faecalis | E. faecalis (only in anaerobic culture) (blood culture with E.faecalis analyzed previously by another laboratory) | Clamoxyl/vancocin | negative | Cp 25.47 4 copies 16S rDNA |
Mitral valvea | endocarditis mitral valve | Streptococcus mitis group | negative (blood culture not available) | no information | gram pos. Cocci ++ | Cp 22.36 4 copies 16S rDNA |
Tricuspid valvea | endocarditis mitral valve | Streptococcus mitis group | negative (blood culture not available) | no information | gram pos. Cocci ++ | Cp 23.13 4 copies 16S rDNA |
Aortic valve | bicuspid aortic valve endocarditis | Abiotropha defectiva | negative (blood culture not available) | no information | negative | Cp 27.63 4 copies 16S rDNA |
Mitral valve | severe insufficiency of mitral valve | Streptococcus mutans | negative (blood culture not available) | no information | gram pos. Cocci ++ | Cp 27.35 5 copies 16S rDNA |