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Table 1 The MIC distribution of lomitapide against 49 clinical S. aureus strains

From: Antibacterial activities and action mode of anti-hyperlipidemic lomitapide against Staphylococcus aureus

S. aureus

No. of isolates tested

No. (%) of isolates

MIC50 (μM)

MIC90 (μM)

MIC Range

LTP MIC = 12.5 μM

LTP MIC = 25 μM

(μM)

MRSA

33

6 (18.2%)

27 (81.8%)

25

25

12.5–25

MSSA

16

13 (81.3%)

3 (18.7%)

12.5

25

12.5–25

Total

49

19 (38.8%)

30 (61.2%)

25

25

12.5–25

  1. LTP Lomitapide, MIC Minimum inhibitory concentration