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Table 1 Sequence and key properties of N6 and PEGylated N6 analogues

From: C-terminal mini-PEGylation of a marine peptide N6 had potent antibacterial and anti-inflammatory properties against Escherichia coli and Salmonella strains in vitro and in vivo

Peptides Amino acid sequences (N’-C’) Length (residues) MW (Da)
N6 GFAWNVCVYRNGVRVCHRRAN 21 2477.80
N6-NH2-miniPEG miniPEG-GFAWNVCVYRNGVRVCHRRAN 21 2620.93
N6-NH2-PEG6 PEG6-GFAWNVCVYRNGVRVCHRRAN 21 2811.21
N6-NH2-PEG12 PEG12-GFAWNVCVYRNGVRVCHRRAN 21 3075.54
N6-NH2-PEG24 PEG24-GFAWNVCVYRNGVRVCHRRAN 21 3604.17
N6-COOH-miniPEG GFAWNVCVYRNGVRVCHRRAN-miniPEG 21 2620.93
N6-Cys7-miniPEG GFAWNV-miniPEG-CVYRNGVRVCHRRAN 21 2620.93
N6-Cys16-miniPEG GFAWNVCVYRNGVRVC-miniPEG-HRRAN 21 2620.93
  1. miniPEG means HO(CH2CH2O)2H; PEG6 means HO(CH2CH2O)6H; PEG12 means HO(CH2CH2O)12H; PEG24 means HO(CH2CH2O)24H