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Fig. 1 | BMC Microbiology

Fig. 1

From: Mutations in SilS and CusS/OmpC represent different routes to achieve high level silver ion tolerance in Klebsiella pneumoniae

Fig. 1

K. pneumoniae strains containing the sil operon can adapt to the presence of AgNO3. A MIC values for AgNO3 and AgSD of pre-exposure (Wildtype), repeatedly passaged in blank media without AgNO3 (Passaged), passaged in increasing concentrations of AgNO3 (SW adapted), and challenged with a single high dose (400 mg/L) of AgNO3 (HD adapted) strains. B Time kill showing generation of increased silver tolerance after 24 h exposure to above MIC concentration of AgNO3 (64 mg/L) for two strains (NCTC 13443 and KPUK04a) which contained a plasmid with the sil operon. Those strains (CFI_124_NDM1OXA232 and CFI_134_NDM1) which did not possess a sil operon containing plasmid died after 6 h exposure

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