Fig. 4

The overview of characteristics and correlations of microbiota and lipid metabolism. A PCA diagrams of metabolite and microbiota in the stool samples based on PC1, PC2 and PC3 values among the indicated groups (Ctr, M, MD). B PCA diagrams of metabolite in the stool samples based on PC1 and PC2 values among the indicated groups. C PCA diagrams of lipid metabolism on a series of levels including phylum, class, order, family, genus and species. D-F Sperman correlation-based hierarchical clustering analysis revealed the diversity in gut microbiota and lipid metabolism between Ctr and MD (D), Ctr and M (E), MD and M (F). *, P < 0.05