Fig. 3From: Celastrol mitigates staphyloxanthin biosynthesis and biofilm formation in Staphylococcus aureus via targeting key regulators of virulence; in vitro and in vivo approach(A) Celastrol decreased production of STX as well as its intermediates (4–4’diapophytoene 4,4`-diaponeurosporene and 4–4` diaponeurosporenic acid). (B) LC-MS/MS of accumulated farnesyl diphosphate in celastrol treated S. aureus. (C) Molecular docking analysis of celastrol with CrtM by ribbon 3D-structure. Data shown represent the mean ± standard of error from triplicate experiments. A P value < 0.05 was considered statistically significant using Student’s t testBack to article page