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Fig. 3 | BMC Microbiology

Fig. 3

From: Celastrol mitigates staphyloxanthin biosynthesis and biofilm formation in Staphylococcus aureus via targeting key regulators of virulence; in vitro and in vivo approach

Fig. 3

(A) Celastrol decreased production of STX as well as its intermediates (4–4’diapophytoene 4,4`-diaponeurosporene and 4–4` diaponeurosporenic acid). (B) LC-MS/MS of accumulated farnesyl diphosphate in celastrol treated S. aureus. (C) Molecular docking analysis of celastrol with CrtM by ribbon 3D-structure. Data shown represent the mean ± standard of error from triplicate experiments. A P value < 0.05 was considered statistically significant using Student’s t test

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