Characterization of Escherichia coli isolated from urinary tract infection and association between virulence expression and antimicrobial susceptibility

Table 4 Isolates used for expression assay and their virulence profile, phylogroup, and real time PCR analysis

Isolates	MIC (µg/mL)		Virulence profile	Phylogroup	^aFold change for Cax (decreased expression level)	^aFold change for CIP (decreased expression level)
Isolates	Cax	CIP	Virulence profile	Phylogroup	^aFold change for Cax (decreased expression level)	^aFold change for CIP (decreased expression level)
U41	0.06	0.03	cnf-pap-hlyA	B2	0.05 (20)	0.22 (4.54)
U51	0.12	0.03	cnf-hlyA	B2	0.17 (5.89)	0.16 (6.25)
U91	0.06	0.016	hlyA	F	0.3 (3.33)	0.67 (1.49)
U66	0.25	0.016	cnf-pap-hlyA	B2	0.4 (2.5)	0.95 (1.05)
U92	0.12	0.016	cnf-pap-hlyA	B2	0.02 (50)	0.12 (8.33)
U47	0.12	0.03	hlyA-pap	E	0.97 (1.03)	0.53 (1.89)
U56	0.12	0.03	hlyA-pap	D	0.06 (16.67)	0.14 (7.14)

^aThe reported data are fold changes in expression of hlyA after exposure to 0.25 MIC ceftriaxone (Cax) and ciprofloxacin (CIP)
Significant changes were seen when compared with the control (no antibiotics) (P < 0.05)

ISSN: 1471-2180