Fig. 2

Analysis of fermentation of wild type Streptomyces sp. 139, mutant strain D2 and C2. Blue: wild-type strain; red: strain D2; green: strain C2. A The competitive binding activities of the fermentation supernatant with IL-1 for IL-1R. Samples were collected at 96 h. B The production of Ebosin at 96 h from Streptomyces sp. 139, Strain D2 and Strain C2. C pH of the fermentation process at different times. D Wet weight of mycelium of fermentation broth sampled at different time points