From: Anti-leishmanial effects of resveratrol and resveratrol nanoemulsion on Leishmania major
Groups | Concentration | MQa infectivity (%) | Number of amastigotes | MQ infectivity (%) | Number of amastigotes | MQ infectivity (%) | Number of amastigotes |
---|---|---|---|---|---|---|---|
0 h (Before treatment) | 24Â h | 48Â h | |||||
Resveratrol | 50 µg/mL | 76.4 | 17.6 | 68.4* | 12.5 | 55.3 | 9.8* |
100 µg/mL | 81.0 | 18.3 | 56.2* | 12.1 | 41.9* | 9.5* | |
200 µg/mL | 78.3 | 18.0 | 42.6* | 6.7* | 35.5* | 2.4* | |
400 µg/mL | 79.6 | 16.2 | 31.4* | 3.3* | 25.8* | 0.5** | |
RNE | 50 µg/mL | 78.4 | 15.8 | 67.8* | 11.6* | 53.8 | 6.7* |
100 µg/mL | 87.5 | 17.3 | 54.2* | 7.3* | 43.0* | 0.6** | |
200 µg/mL | 84.5 | 17.6 | 34.3* | 2.6* | 26.2* | 0.0** | |
400 µg/mL | 77.0 | 17.0 | 22.5** | 0.0** | 17.4** | 0.0** | |
Amphotericin B | 20 µg/mL | 73.4 | 15.7 | 34.5* | 4.3* | 42.7* | 0.4** |
PBS | 7.23 μM | 74.5 | 16.3 | 81.7 | 15.2 | 63.2 | 14.6 |
DMSO | 6.73 μM | 80.3 | 16.3 | 73.5 | 13.6 | 67.7 | 12.9 |