Fig. 3

Time-killing curve of thiazolidione derivatives combined with ampicillin, vancomycin, linezolid, or daptomycin against E. faecium EF16M64. Antibacterial activities of a H2-60 and b H2-81 on E. faecim EF16M64 planktonic cells were determined by time-killing study. The data presented was the average of three independent repeats (mean ± SD). All chemicals or antimicrobials were used at 4 × MIC. AMP ampicillin, DAP daptomycin, VAN vancomycin, LZD linezolid