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Fig. 3 | BMC Microbiology

Fig. 3

From: Proteome and secretome profiling of zinc availability in Cryptococcus neoformans identifies Wos2 as a subtle influencer of fungal virulence determinants

Fig. 3

Cellular proteome profiling of zinc limitation in C. neoformans. A PCA plot of C. neoformans biological replicates under limited (grey) and replete (purple) conditions; clustering based on growth conditions (component 1) and biological variability (component 2). B Volcano plot depicting all proteins identified under zinc-limited and -replete (10 μM) conditions, highlighting proteins with significant increases or decreases in abundance during limited (grey) and replete (purple) conditions. Student’s t-test, p-value ≤ 0.05; FDR = 0.05; S0 = 1. C 1D annotation enrichment based on Gene Ontology Biological Processes (Student’s t-test, p-value ≤ 0.05; FDR = 0.05; − 0.5 < score < 0.5). Experiment performed in biological triplicate

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