IgG antibody titers against SARS-CoV-2 nucleocapsid protein correlate with the severity of COVID-19 patients

BMC Microbiology

Table 3 Sensitivity and specificity of SARS-CoV-2-N-IgG ELISA with reference to the SARS-CoV-2 Spike S1 Protein IgG Antibody ELISA Kit

	SARS-CoV-2 Spike S1 Protein IgG antibody ELISA Kit	r-SARS-CoV-2-N based IgG ELISA	Total
	SARS-CoV-2 Spike S1 Protein IgG antibody ELISA Kit	Positive Negative	Total
Positive	178	0	178
Negative	2	182	184
Total	180	182	362
Concordance ^a: 99.4%		Sensitivity ^b: 100%	Specificity ^c: 98.9%

χ² = 0.678, p > 0.05
The sensitivity and specificity of the SARS-CoV-2-N IgG ELISA compared to the SARS-CoV-2 spike S1 protein IgG antibody kit
a) (The number of positive samples detected by both methods + the number of samples determined to be negative by both methods)/the total number × 100
b) True positive (true positive + false negative) × 100
c) True negative (true negative – false positive) × 100

ISSN: 1471-2180