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Table.3 Agreements within and between susceptibility assays of Nocardia spp. isolates with TMP-SMX

From: Evaluation of antimicrobial susceptibility testing of Nocardia spp. isolates by broth microdilution with resazurin and spectrophotometry

Agreement

aBroth Microdilution Method

Disk Diffusion

Gold Standard

Resazurin

OD

± 1

± 2

± 1

± 2

± 1

± 2

Essential

 Intra-reading

82.0

97.0

73.1

88.5

81.8

93.9

dn.a.

bInter-reading

71.7

89.8

75.0

88.6

dn.a.

  b,cPearson’s r

0.50

0.42

0.36

0.44

dn.a.

  (95% CI)

(0.36–0.62)

(0.26–0.55)

(0.20–0.45)

(0.30–0.57)

Categorical

 Intra-reading

95.5

88.5

86.2

86.2

99.2

97.0

100.0

bInter-reading

81.1

91.3

91.7

93.9

97.7

  bVery Major Errors

0.0

0.0

8.33

6.06

2.27

  bMajor Errors

18.9

8.66

0.0

0.0

0.0

  1. aBMD method concordant results considering ±1 or ± 2 two-fold dilutions
  2. bCompared with the Gold Standard BMD method
  3. cP < 0.0001 for all comparisons
  4. dNot applicable