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Table 2 HPLC quantification of antimicrobials released from gelatin hydrogel containing paenipeptin and clarithromycin

From: Enzymatically-crosslinked gelatin hydrogels containing paenipeptin and clarithromycin against carbapenem-resistant pathogen in murine skin wound infection

Time (h) Paenipeptin analogue 1 Clarithromycin
μg Release percentage (%) μg Release percentage (%)
3 21.85 ± 2.58 24.28 17.00 ± 0.42 18.89
4 27.91 ± 2.45 31.00 19.34 ± 0.43 21.49
6 38.09 ± 1.87 42.33 26.51 ± 1.04 29.45
8 42.51 ± 1.68 47.24 29.61 ± 2.07 32.90
10 50.35 ± 0.60 55.95 35.02 ± 1.50 38.91
24 67.89 ± 7.47 75.43 48.29 ± 5.84 53.66