Skip to main content

Table 5 Characteristics of the included datasets in meta-analysis

From: The composition of lung microbiome in lung cancer: a systematic review and meta-analysis

Study

Population

Accession number

16S region

Sequencing platform

CCN

Cases

Controls

Age (y/o)

Study 1

Apopa et al. [23]

AF & EU

PRJNA472758

27 F & 519R

Illumina MiSeq

14

9

5

50–80

Study 2

Nejman et al. [47]

IL

PRJNA624822

*

*

476

245

231

NA

Study 3

Yu et al. [24]

IT 1

PRJNA303190

V3–V4

Illumina MiSeq

257

50

207

40–80

Study 4

-

IT 2

PRJNA327258

NA

Illumina MiSeq

53

27

26

40–80

Study 5

Kovaleva et al. [48]

RU

PRJNA647170

V3–V4

Illumina MiSeq

49

25

24

62\(\pm 10\)

Total

    

849

356

493

 
  1. CCN: Case-Control Number; Cases: either AC (lung adenocarcinoma) or SCC (lung squamous cell carcinoma); Controls: tumor-adjacent normal tissues; y/o: years old; AF & EU: Africa & Europe; IL: Israel; IT: Italy; RU: Russia; NA: Not Available; * Five regions of the 16S rRNA gene were amplified and sequenced on Illumina HiSeq, MiSeq or NextSeq