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Table 5 Characteristics of the included datasets in meta-analysis

From: The composition of lung microbiome in lung cancer: a systematic review and meta-analysis

Study Population Accession number 16S region Sequencing platform CCN Cases Controls Age (y/o)
Study 1
Apopa et al. [23]
AF & EU PRJNA472758 27 F & 519R Illumina MiSeq 14 9 5 50–80
Study 2
Nejman et al. [47]
IL PRJNA624822 * * 476 245 231 NA
Study 3
Yu et al. [24]
IT 1 PRJNA303190 V3–V4 Illumina MiSeq 257 50 207 40–80
Study 4
-
IT 2 PRJNA327258 NA Illumina MiSeq 53 27 26 40–80
Study 5
Kovaleva et al. [48]
RU PRJNA647170 V3–V4 Illumina MiSeq 49 25 24 62\(\pm 10\)
Total      849 356 493  
  1. CCN: Case-Control Number; Cases: either AC (lung adenocarcinoma) or SCC (lung squamous cell carcinoma); Controls: tumor-adjacent normal tissues; y/o: years old; AF & EU: Africa & Europe; IL: Israel; IT: Italy; RU: Russia; NA: Not Available; * Five regions of the 16S rRNA gene were amplified and sequenced on Illumina HiSeq, MiSeq or NextSeq