Fig. 5

Bacterial diversity of tumor, normal adjacent and healthy control tissues following decontamination. a-b The α- and β- diversity results of formalin-fixed paraffin embedded (FFPE) tissues at genus level following decontamination are shown for the datasets obtained by a non-nested (a) and a nested (b) polymerase chain reaction (PCR) approach. The dot plots show the bacterial biodiversity measured by Shannon and Chao1 diversity indices. Principal Coordinates Analysis (PCoA) plots illustrate the bacterial composition of tissue using weighted UniFrac and Bray-Curtis dissimilarity. Abbreviations for level of significance: n.s. not significant