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Table 4 Sensitivity and specificity according to various cutoff values for the -ΔCt of pharyngeal F.n in qPCR to predict COVID-19

From: Beware of pharyngeal Fusobacterium nucleatum in COVID-19

-ΔCt cutoff

Sensitivity (95% CI)

Specificity (95% CI)

≥ −9.41

100 (87.7 ~ 100.0)

0 (0.0 ~ 30.8)

> − 9.41

100 (87.7 ~ 100.0)

10 (0.3 ~ 44.5)

> − 9.03

96.43 (81.7 ~ 99.9)

10 (0.3 ~ 44.5)

> − 2.78

96.43 (81.7 ~ 99.9)

20 (2.5 ~ 55.6)

> − 1.42

89.29 (71.8 ~ 97.7)

20 (2.5 ~ 55.6)

> − 1.27

89.29 (71.8 ~ 97.7)

30 (6.7 ~ 65.2)

> − 0.88

85.71 (67.3 ~ 96.0)

30 (6.7 ~ 65.2)

> 0.27

85.71 (67.3 ~ 96.0)

50 (18.7 ~ 81.3)

> 1.91

78.57 (59.0 ~ 91.7)

50 (18.7 ~ 81.3)

>  2.40

78.57 (59.0 ~ 91.7)

90 (55.5 ~ 99.7)

>  2.96

71.43 (51.3 ~ 86.8)

90 (55.5 ~ 99.7)

>  3.50

71.43 (51.3 ~ 86.8)

100 (69.2 ~ 100.0)

>  16.52

0 (0.0 ~ 12.3)

100 (69.2 ~ 100.0)

  1. Abbreviations: Ct cycle threshold, F. n Fusobacterium nucleatum, qPCR quantitative real-time polymerase chain reaction, COVID-19 coronavirus disease 2019, CI confidence interval