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Table 4 Sensitivity and specificity according to various cutoff values for the -ΔCt of pharyngeal F.n in qPCR to predict COVID-19

From: Beware of pharyngeal Fusobacterium nucleatum in COVID-19

-ΔCt cutoff Sensitivity (95% CI) Specificity (95% CI)
≥ −9.41 100 (87.7 ~ 100.0) 0 (0.0 ~ 30.8)
> − 9.41 100 (87.7 ~ 100.0) 10 (0.3 ~ 44.5)
> − 9.03 96.43 (81.7 ~ 99.9) 10 (0.3 ~ 44.5)
> − 2.78 96.43 (81.7 ~ 99.9) 20 (2.5 ~ 55.6)
> − 1.42 89.29 (71.8 ~ 97.7) 20 (2.5 ~ 55.6)
> − 1.27 89.29 (71.8 ~ 97.7) 30 (6.7 ~ 65.2)
> − 0.88 85.71 (67.3 ~ 96.0) 30 (6.7 ~ 65.2)
> 0.27 85.71 (67.3 ~ 96.0) 50 (18.7 ~ 81.3)
> 1.91 78.57 (59.0 ~ 91.7) 50 (18.7 ~ 81.3)
>  2.40 78.57 (59.0 ~ 91.7) 90 (55.5 ~ 99.7)
>  2.96 71.43 (51.3 ~ 86.8) 90 (55.5 ~ 99.7)
>  3.50 71.43 (51.3 ~ 86.8) 100 (69.2 ~ 100.0)
>  16.52 0 (0.0 ~ 12.3) 100 (69.2 ~ 100.0)
  1. Abbreviations: Ct cycle threshold, F. n Fusobacterium nucleatum, qPCR quantitative real-time polymerase chain reaction, COVID-19 coronavirus disease 2019, CI confidence interval