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Table 1 Performance of Carba 5 assay using isolates from the retrospective analysis

From: Application of a multiplex immunochromatographic assay for rapid identification of carbapenemases in a clinical microbiology laboratory: performance and turn-around-time evaluation of NG-test Carba 5

Target carbapenemase

Organism group

No. of positive tests / total no. of isolates

Sensitivity

(95% CI)

Specificity

(95% CI)

Enterobacteriaceae

Pseudomonas

species

KPC

  

30/30

100 (88.43–100)

100 (94.94–100)

 KPC-2

30

 

NDM

  

26/26

100 (86.77–100)

100 (95.20–100)

 NDM-1

24

 

 NDM-5

1

 

 NDM-7

1

 

VIM

  

12/13

92.31 (63.97–99.81)

100 (95.89–100)

 VIM-1

11

 

 VIM-2

1

1

OXA-48-like

  

5/5

100 (47.82–100)

100 (96.23–100)

 OXA-48

4

 

 OXA-181

1

 

IMP

  

3/3

100 (29.24–100)

100 (96.31–100)

 IMP-1

1

 

 IMP-6

 

2

NDM + OXA-48-like

  

1/1

100 (2.50–100)

100 (96.38–100)

 NDM-5 + OXA-181

 1

 

Overall

76

2

77/78

98.72 (93.06–99.97)

100 (85.18–100)

Non-carbapenemase producers

21

2

23