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Fig. 2 | BMC Microbiology

Fig. 2

From: Reproductive tract microbiota of women in childbearing age shifts upon gynecological infections and menstrual cycle

Fig. 2

The permutation of the 111 samples in a 3-dimensional space constructed by principal coordinates analysis (PCoA) based on Unweighted UniFrac distance. a upper: Samples in Normal group were clustered together (green dots in the rectangle) and had significant shorter genetic distance apart from samples in the other groups of gynecological infections. a lower: Unweighted UniFrac distance (beta diversity) of within-group (Normal) was significantly shorter versus that of between-groups (Normal vs the other gynecological infections). b upper: samples from in pregnancy group were clustered together (red dots in the rectangle) apart from samples in groups of with and without childbearing. b lower: Unweighted UniFrac distance of within-group (in pregnancy) was significantly shorter versus that of between-groups (in pregnancy vs with or without childbearing). c upper: samples from in pregnancy group were clustered together (blue dots in the rectangle) apart from samples in groups of luteal and follicular phase. c lower: Unweighted UniFrac distance of within-group (in pregnancy) was significantly shorter versus that of between-groups (in pregnancy vs in luteal or follicular phase). In a, b and c lower, the boxes are interquartile range (IQR) of Unweighted UniFrac distance; median values of distance are the bands within the boxes; the line terminals outside the boxes are upper and lower endpoint of the data; crosses are outliers. The tests of significance were performed using a two-sided Student’s two-sample t-test. The nonparametric P-values were calculated using 999 Monte Carlo permutations

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