Disturbed microbial ecology in Alzheimer’s disease: evidence from the gut microbiota and fecal metabolome

BMC Microbiology

Table 3 Association of peripheral inflammatory cytokines and Alzheimer’s disease risk

Cytokines	Number of subjects	Mean		Median		P value^a
Cytokines	AD/NC	AD	NC	AD	NC	P value^a
IL-6	18/41	3.57	2.75	1.44	1.63	0.792
IL-8	18/43	7.38	6.77	6.09	5.99	0.794
IL-10	18/43	1.08	1.85	1.01	1.18	0.315
G-CSF	19/43	1.28	1.84	1.27	1.59	0.008
IL-7	19/43	2.14	2.22	2.05	2.05	0.667
IL-8	19/43	3.17	3.29	2.40	3.15	0.113
IL-12	19/42	1.32	1.50	0.95	0.95	0.849
IFN-γ	19/42	0.97	1.75	0.66	1.40	0.007
MCP-1	19/43	6.87	8.27	6.85	7.72	0.172
MIP-1β	19/43	8.33	10.95	6.45	8.28	0.194
TNF-α	19/39	2.27	2.67	1.61	2.12	0.314

AD Alzheimer’s disease, NC cognitively normal control
^a Comparison between AD group and NC group of median, using Mann-Whitney U test

ISSN: 1471-2180