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Table 3 Association of peripheral inflammatory cytokines and Alzheimer’s disease risk

From: Disturbed microbial ecology in Alzheimer’s disease: evidence from the gut microbiota and fecal metabolome

Cytokines Number of subjects Mean Median P valuea
AD/NC AD NC AD NC
IL-6 18/41 3.57 2.75 1.44 1.63 0.792
IL-8 18/43 7.38 6.77 6.09 5.99 0.794
IL-10 18/43 1.08 1.85 1.01 1.18 0.315
G-CSF 19/43 1.28 1.84 1.27 1.59 0.008
IL-7 19/43 2.14 2.22 2.05 2.05 0.667
IL-8 19/43 3.17 3.29 2.40 3.15 0.113
IL-12 19/42 1.32 1.50 0.95 0.95 0.849
IFN-γ 19/42 0.97 1.75 0.66 1.40 0.007
MCP-1 19/43 6.87 8.27 6.85 7.72 0.172
MIP-1β 19/43 8.33 10.95 6.45 8.28 0.194
TNF-α 19/39 2.27 2.67 1.61 2.12 0.314
  1. AD Alzheimer’s disease, NC cognitively normal control
  2. a Comparison between AD group and NC group of median, using Mann-Whitney U test