Fig. 3
From: Associations between the gut microbiome and metabolome in early life
Pairwise Spearman correlation of concentration-fitted metabolites and genus-level taxonomic abundances for 6-weeks (panel A, N = 158) and 12-months (panel B, N = 282) infants. Left panel displays the overall correlation pattern, where non-significant correlations are not colored (false discovery rate (FDR) controlled q-value < 0.05). Right panel displays the same heatmap restricted to taxa and metabolites selected by the sparse CCA procedure. Additionally, correlation coefficient of the first sCCA variate pair, bootstrapped 95% confidence interval and permutation p-value are also reported. Significant microbiome-metabolome correlation was observed at both time points, however no significant difference was found between the time points