Table 4 Bacteria as carriers for colorectal cancer therapeutic agents
From: Colorectal cancer treatment using bacteria: focus on molecular mechanisms
Microorganism | Gram Information | Combined agent | References |
|---|---|---|---|
Lysteria monocytogenes | Gram-positive | Anti-cancer vaccines | [68] |
Salmonella typhimurium | Gram-negative | Cytokines like IL-2, CCL21, Cytotoxic proteins, enzymes, vaccines | |
E.coli Nissle 1917 | Gram negative | P53 and Tum-5 protein | [64] |
Clostridium novyi-NT | Gram-positive | Liposomal doxorubicin | [73] |