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Table 4 Bacteria as carriers for colorectal cancer therapeutic agents

From: Colorectal cancer treatment using bacteria: focus on molecular mechanisms

Microorganism Gram Information Combined agent References
Lysteria monocytogenes Gram-positive Anti-cancer vaccines [68]
Salmonella typhimurium Gram-negative Cytokines like IL-2, CCL21, Cytotoxic proteins, enzymes, vaccines [71, 74,75,76]
E.coli Nissle 1917 Gram negative P53 and Tum-5 protein [64]
Clostridium novyi-NT Gram-positive Liposomal doxorubicin [73]