Fig. 1
From: Colorectal cancer treatment using bacteria: focus on molecular mechanisms
The colorectal cancer bacterial therapy can be performed by means of bacterial whole cell such as probiotics or bacterial-associated peptides like bacteriocins or bacterial toxins. The anticancer effect of this treatment can be achieved by different mechanisms: 1) Pore forming in the cell membrane 2) Induction of apoptosis 3) DNA alkylation 4) RNase activity 5) TNF-α production 6) Inhibition of metastasis [10, 29]