Table 2 Performance of routine culture and pre-processing using tissue homogenizer using clinical infection as reference standard
From: Pre-processing tissue specimens with a tissue homogenizer: clinical and microbiological evaluation
Sensitivity (95 %CI) | Specificity (95 %CI) | |
|---|---|---|
All tissues (n = 104) | ||
Routine procedure | 89.1 (80.9 to 97.3) | 61.2 (48.3 to 74.1) |
With pre- processing | 83.6 (73.8 to 93.3) | 63.3 (50.1 to 76.0) |
Periprosthetic tissues only (n = 42) | ||
Routine procedure | 96.3 (91.3 to 100.0) | 93.3 (86.7 to 99.9) |
With pre- processing | 77.8 (66.8 to 88.8) | 93.3 (86.7 to 99.9) |
Bone tissues only (n = 41) | ||
Routine procedure | 90 (82.1 to 97.9) | 71.4 (59.5 to 83.3) |
With pre- processing | 95 (89.2 to 100.0) | 76.2 (64.9 to 87.4) |
Soft tissues only (n = 63) | ||
Routine procedure | 88.6 (80.2 to 97.0) | 53.6 (40.4 to 66.8) |
With pre- processing | 77.1 (66.0 to 88.2) | 53.6 (40.4 to 66.8) |
Only tissues without possible commensals (ENT and GI-tract) (n = 88) | ||
Routine procedure | 87.8 (79.2 to 96.4) | 76.9 (65.8 to 88.0) |
With pre- processing | 81.6 (71.4 to 100.0) | 79.5 (68.8 to 90.2) |