Skip to main content

Table 4 The total frequency and percentages of the AMR genes in 189 genomes of A. baumannii isolated from Germany

From: WGS based analysis of acquired antimicrobial resistance in human and non-human Acinetobacter baumannii isolates from a German perspective

  AMR gene Mechanism Frequency a
(NCBI+WGS)
Total (189) % Predicted phenotype
1 ant(3″)-IIa Antibiotic inactivation 104 + 0 104 55% Aminoglycosides
2 blaADC.25 Ambler class C
beta-lactamase
2 + 71 73 38.6% Cephalosporins
3 blaOXA-23 Ambler class D
beta-lactamase
43 + 12 55 29% Carbapenems
4 blaOXA-66
(blaOXA-51-like)
Ambler class D
beta-lactamase
40 + 10 50 26.5% Carbapenems
5 sul2 Antibiotic target replacement 47 + 2 49 26% Sulfonamides
6 aph(3″)-Ib Antibiotic inactivation 48 + 0 48 25.3% Aminoglycosides
7 aph(6)-Id Antibiotic inactivation 45 + 9 44 23.3% Aminoglycosides
8 tet. B Antibiotic efflux 38 + 9 37 19.5% Tetracycline
9 mph(E) Enzymes inactivation 34 + 2 36 19% Macrolide
10 msr(E) Antibiotic target protection 33 + 3 36 19% Macrolide
11 aph(3″)-Ia Antibiotic inactivation 28 + 0 34 18% Aminoglycosides
12 sul1 Antibiotic target replacement 22 + 3 25 13.2% Sulfonamides
13 aph(3′)-VIa Antibiotic inactivation 24 + 0 24 12.6% Aminoglycosides
14 blaTEM Antibiotic inactivation 20 + 3 23 12% Cephalosporins
15 blaADC-73 Ambler class C
beta-lactamase
19 + 0 19 10% Cephalosporins
  1. afrequency of genes in genomes deposited in the NCBI (104) and 85 WGS data at our laboratory