Table 4 The total frequency and percentages of the AMR genes in 189 genomes of A. baumannii isolated from Germany
| AMR gene | Mechanism |
Frequency a (NCBI+WGS) | Total (189) | % | Predicted phenotype | |
|---|---|---|---|---|---|---|
| 1 | ant(3″)-IIa | Antibiotic inactivation | 104 + 0 | 104 | 55% | Aminoglycosides |
| 2 | blaADC.25 |
Ambler class C beta-lactamase | 2 + 71 | 73 | 38.6% | Cephalosporins |
| 3 | blaOXA-23 |
Ambler class D beta-lactamase | 43 + 12 | 55 | 29% | Carbapenems |
| 4 |
blaOXA-66 (blaOXA-51-like) |
Ambler class D beta-lactamase | 40 + 10 | 50 | 26.5% | Carbapenems |
| 5 | sul2 | Antibiotic target replacement | 47 + 2 | 49 | 26% | Sulfonamides |
| 6 | aph(3″)-Ib | Antibiotic inactivation | 48 + 0 | 48 | 25.3% | Aminoglycosides |
| 7 | aph(6)-Id | Antibiotic inactivation | 45 + 9 | 44 | 23.3% | Aminoglycosides |
| 8 | tet. B | Antibiotic efflux | 38 + 9 | 37 | 19.5% | Tetracycline |
| 9 | mph(E) | Enzymes inactivation | 34 + 2 | 36 | 19% | Macrolide |
| 10 | msr(E) | Antibiotic target protection | 33 + 3 | 36 | 19% | Macrolide |
| 11 | aph(3″)-Ia | Antibiotic inactivation | 28 + 0 | 34 | 18% | Aminoglycosides |
| 12 | sul1 | Antibiotic target replacement | 22 + 3 | 25 | 13.2% | Sulfonamides |
| 13 | aph(3′)-VIa | Antibiotic inactivation | 24 + 0 | 24 | 12.6% | Aminoglycosides |
| 14 | blaTEM | Antibiotic inactivation | 20 + 3 | 23 | 12% | Cephalosporins |
| 15 | blaADC-73 |
Ambler class C beta-lactamase | 19 + 0 | 19 | 10% | Cephalosporins |