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Table 1 List of acquired β-lactamases resistance genes identified in A. baumannii isolates (n = 85) from humans and dried milk based on WGS data using ResFinder database

From: WGS based analysis of acquired antimicrobial resistance in human and non-human Acinetobacter baumannii isolates from a German perspective

Mechanism AMR genes Group No. (%) Source Resistance pattern
Amber class A β-lactamases blaTEM.1D_1 TEM 3 (3.5%) Human PIP-PIT/CTX-CAZ-CAA-CTA-CEP /IMP-MER-ERT
blaCARB.5_1 CARB-5 3 (3.5%) Human
Amber class C β-lactamases blaADC.25_1 ADC 14 (16.5%) Human 11 [PIP-PIT/CTX-CAZ-CTA-CEP/IMP-MER-ERT]
71 (83.5%) Milk powder 66 [CTX], 10 [ERT]
Amber class D β-lactamases blaOXA.23_1 OXA-23 12 (14%) Human 12 [PIP-PIT/CTX-CAZ-CTA-CE/IMP-MER-ERT], 10 [CAA]
blaOXA.120_1 OXA-51 2 (2.3%) Milk powder CTX
blaOXA.203_1 1 (1.2%) Milk powder CTX
blaOXA.259_1 1 (1.2%) Milk powder CTX-ERT
blaOXA.343_1 4 (4.7%) Milk powder
blaOXA.346_1 4 (4.7%) Milk powder 4 [CTX], 2 [ERT]
blaOXA.380_1 2 (2.3%) Milk powder CTX
blaOXA.386_1 1 (1.2%) Milk powder CTX
blaOXA.424_1 1 (1.2%) Milk powder CTX-ERT
blaOXA.430_1 24 (28.2%) Milk powder 24 [CTX], 4 [ERT]
blaOXA.431_1 1 (1.2%) Milk powder CTX
blaOXA.51_1 1 (1.2%) Milk powder CTX
blaOXA.64_1 9 (10.5%) Milk powder 8[CTX]/1 [COL]
blaOXA.66_1 10 (11.8%) Human 10 [PIP-PIT/CTX-CAZ-CTA/IMP-MER-ERT], 9 [CEP], 7 [CAA].
blaOXA.69_1 1 (1.2%) Human PIP-PIT/CTX-CAZ-CAA-CTA-CEP /IMP-MER-ERT
blaOXA.72_1 1 (1.2%) Human PIP-PIT/CTX-CAZ-CTA/IMP-MER-ERT
blaOXA.91_1 2 (2.2%) Human PIP-PIT/CTX-CAZ-CAA-CTA-CEP /IMP-MER-ERT
19 (22.3%) Milk powder CTX
blaOXA.510_1 single
variant
1 (1.2%) Milk powder CTX
blaOXA.521_1 single
variant
1 (1.2%) Human PIP-PIT/CTX-CAZ-CAA-CTA-CEP/IMP-MER-ERT
  1. AMR antimicrobial resistance gene, PIP piperacillin, PIT piperacillin/tazobactam, CTX cefotaxime, CAZ ceftazidime, CAA ceftazidime/avibactam, CEP cefepime; CTA ceftolozane/tazobactam, IMP imipenem, MER meropenem, ERT ertapenem