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Fig. 3 | BMC Microbiology

Fig. 3

From: AgNP-PVP-meglumine antimoniate nanocomposite reduces Leishmania amazonensis infection in macrophages

Fig. 3

Transmission electron micrographs of Leishmania amazonensis promastigotes after treatment with the AgNP-PVP-MA nanocomposite (AgNP to 1 %, 0.1 g of PVP and 50 µg/mL of MA) for 96 h. Promastigote forms without treatment (negative control), with typical morphology (A). Promastigotes displaying chromatin condensation in the nuclear periphery [arrows] (B). Changes in parasite vesicles [+], with possible accumulation of the nanocomposite [*], and the presence of myelin-like structures in mitochondria [] (C). Plasma membrane rupture [] and the presence of vesicles containing electrondense material [asterisks] at the edges of the nucleus [N] (D). Altered vesicles [+] and the presence of myelin-like structures in the Golgi complex [] (E). Parasite flagellar membrane changes [] (F). N: Nucleus. M: Mitochondrion. F: Flagellum. FP: Flagellar pocket. GC: Golgi complex. V: Vesicles. K: Kinetoplast

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