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Table 5 Correlation between stool patterns and plasma and fecal fatty acids

From: Stool pattern is associated with not only the prevalence of tumorigenic bacteria isolated from fecal matter but also plasma and fecal fatty acids in healthy Japanese adults

 

Structure

n

Unit

Median

Interquartile range

Stool status pattern

1

2

3

Plasma

 Lauric acid

C12:0

221

μg/ml

1.8

(1.2 to 2.7)

0.02

 

−0.05

−0.05

 Myristic acid

C14:0

223

μg/ml

21.4

(16.4 to 28.8)

−0.09

 

0.03

− 0.07

 Palmitic acid

C16:0

223

μg/ml

668.7

(594.6 to 749.7)

−0.07

 

0.06

−0.04

 Stearic acid

C18:0

223

μg/ml

227.3

(203.3 to 259.3)

−0.07

 

0.07

−0.03

 Arachidic acid

C20:0

223

μg/ml

8.9

(7.8 to 10.0)

−0.11

 

− 0.06

− 0.05

 Behenic acid

C22:0

223

μg/ml

21.7

(18.9 to 24.9)

0.00

 

−0.02

− 0.03

 Lignoceric acid

C24:0

223

μg/ml

19.4

(0.8 to 22.8)

0.03

 

−0.02

−0.02

 Total saturated fatty acids

 

223

μg/ml

969.9

(862.4 to 1092.5)

−0.07

 

0.06

−0.04

 Oleic acid

C18:1n-9

223

μg/ml

568.6

(485.6 to 659.0)

−0.11

 

0.10

−0.01

 Eicosenoic acid

C20:1n-9

223

μg/ml

4.2

(3.5 to 5.3)

−0.16

*

0.06

0.00

 5,8,11-Eicosatrienoic acid

C20:3n-9

217

μg/ml

2.4

(1.5 to 3.2)

−0.05

 

−0.03

0.07

 Erucic acid

C22:1n-9

48

μg/ml

1.2

(1.1 to 1.3)

−0.04

 

−0.04

− 0.12

 Nervonic acid

C24:1n-9

223

μg/ml

36.1

(1.6 to 42.2)

−0.03

 

0.04

−0.10

 Total n-9 fatty acids

 

223

μg/ml

610.7

(514.5 to 701.9)

−0.12

 

0.10

−0.01

 Palmitoleic acid

C16:1n-7

223

μg/ml

48.7

(38.1 to 60.7)

−0.10

 

0.04

−0.08

 Linoleic acid

C18:2n-6

223

μg/ml

956.8

(846.0 to 1111.3)

−0.02

 

0.05

−0.02

 γ-linolenic acid

C18:3n-6

223

μg/ml

8.9

(5.8 to 12.9)

−0.06

 

−0.03

0.04

 Eicosadienoic acid

C20:2n-6

223

μg/ml

7.2

(6.1 to 8.4)

−0.10

 

0.01

0.02

 Dihomo-gamm-linolenic acid

C20:3n-6

223

μg/ml

38.7

(29.8 to 46.1)

−0.07

 

−0.05

0.05

 Arachidonic acid

C20:4n-6

223

μg/ml

214.8

(184.5 to 249.7)

0.03

 

0.05

−0.01

 Docosatetraenoic acid

C22:4n-6

223

μg/ml

4.8

(3.9 to 5.8)

0.04

 

0.03

0.06

 Total n-6 fatty acids

 

223

μg/ml

1234.0

(1104.4 to 1389.5)

−0.01

 

0.03

−0.01

 Myristoleic acid

C14:1n-5

221

μg/ml

1.2

(0.8 to 1.8)

−0.08

 

0.02

−0.10

 α-linoleic acid

C18:3n-3

223

μg/ml

22.3

(16.7 to 30.0)

−0.14

*

0.03

−0.08

 Eicosapentaenoic acid

C20:5n-3

223

μg/ml

65.9

(43.5 to 98.6)

−0.12

 

− 0.01

−0.12

 Docosapentaenoic acid

C22:5n-3

223

μg/ml

16.5

(0.8 to 21.7)

−0.03

 

0.02

−0.05

 Docosahexaenoic acid

C22:6n-3

223

μg/ml

137.4

(6.4 to 173.7)

−0.04

 

0.03

−0.10

 Total n-3 fatty acids

 

223

μg/ml

236.4

(152.2 to 301.9)

−0.10

 

0.03

−0.11

 Mono fatty acids

 

223

μg/ml

660.3

(560.4 to 756.6)

−0.12

 

0.10

−0.03

 Polyunsaturated fatty acid

 

223

μg/ml

1482.0

(1292.1 to 1667.6)

−0.05

 

0.05

−0.07

 n-3/n-6 fatty acids

 

223

 

0.18

(0.13 to 0.24)

−0.10

 

− 0.01

−0.12

 Total fatty acids

 

223

μg/ml

3093.9

(2749.6 to 3512.7)

−0.07

 

0.07

−0.05

Fecal

 Formate

C1:0

58

mol/g

2.66

(0.83 to 4.59)

0.17

 

−0.10

−0.07

 Acetate

C2:0

161

mol/g

57.41

(44.66 to 67.12)

−0.06

 

0.09

0.06

 Propionate

C3:0

161

mol/g

16.40

(11.59 to 23.96)

−0.30

**

0.15

0.00

 Lactate

C3:0

19

mol/g

0.08

(0.03 to 0.30)

0.04

 

−0.08

0.44

 Isobutyrate

C4:0

161

mol/g

1.57

(0.95 to 2.19)

0.21

**

−0.11

−0.15

 Butyrate

C4:0

161

mol/g

10.30

(6.59 to 17.52)

−0.07

 

0.06

−0.01

 Succinate

C4:0

143

mol/g

0.18

(0.09 to 0.34)

−0.21

**

0.05

0.09

 Isovalerate

C5:0

161

mol/g

1.01

(0.57 to 1.50)

0.27

**

−0.12

−0.14

 Valerate (Pentanoate)

C5:0

160

mol/g

1.36

(0.66 to 2.06)

0.15

*

−0.03

−0.08

 Hexanoate

C6:0

161

mol/g

0.06

(0.02 to 0.28)

0.32

**

−0.07

0.06

 Total SCFA

 

161

mol/g

97.02

(72.12 to 116.97)

−0.13

 

0.11

0.03

  1. Statistical analysis was performed by Spearman’s correlation analysis. The statistical significance p value is indicated as follows: if p < 0.05, single asterisk (*); if p < 0.01 double asterisk (**). If the results presented a positive correlation, the participants with higher adherence to each stool patterns mean to relate higher plasma and fecal fatty acids (conversely, a negative correlation indicates that they mean lower it)