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Table 3 Factors associated with drug-resistance TB

From: Prevalence and molecular characteristics of drug-resistant Mycobacterium tuberculosis in Hainan, China: from 2014 to 2019

Factors Any drug resistant TB (n = 658) MDR-TB (n = 369) XDR-TB (n = 123) Pan-susceptible TB (n = 826) Any drug resistant TB VS Pan-susceptible TB MDR-TB VS Pan-susceptible TB XDR-TB VS Pan-susceptible TB
OR (95%CI) P Adjusted OR (95%CI) P OR (95%CI) P Adjusted OR (95%CI) P OR (95%CI) P Adjusted OR (95%CI) P
Gender
 Male 534 (81.2) 299 (81.0) 97 (78.9) 683 (82.7) Reference     Reference     Reference    
 Female 124 (18.8) 70 (19.0) 26 (21.1) 143 (17.3) 0.83 (0.614,1.121) 0.225    0.82 (0.555,1.209) 0.316    0.673 (0.387,1.172) 0.162   
Age (years)
  ~ 25 84 (12.8) 52 (14.1) 15 (12.2) 121 (14.6) Reference   Reference   Reference   Reference   Reference   Reference  
  ~ 44 173 (26.3) 100 (27.1) 31 (25.2) 202 (24.5) 1.08 (0.737,1.582) 0.694 1.052 (0.720,1.536) 0.795 0.955 (0.588,1.550) 0.852 0.917 (0.568,1.482) 0.725 1.129 (0.540,2.363) 0.747 1.062 (0.511,2.205) 0.873
  ~ 64 311 (47.3) 183 (49.6) 67 (54.5) 324 (39.2) 1.079 (0.753,1.544) 0.679 1.039 (0.730,1.479) 0.833 0.941 (0.598,1.480) 0.791 0.886 (0.568,1.328) 0.593 1.329 (0.674,2.622) 0.412 1.227 (0.629,2.390) 0.549
  > 64 90 (13.7) 34 (9.2) 10 (8.1) 179 (21.7) 0.626 (0.410,0.954) 0.030 0.602 (0.397,0.913) 0.017 0.3 (0.169,0.533) < 0.001 0.277 (0.157,0.486) < 0.001 0.317 (0.128,0.786) 0.013 0.287 (0.117,0.702) 0.006
Treatment history
 New cases 213 (32.4) 71 (19.2) 19 (15.4) 612 (74.1) Reference   Reference   Reference   Reference   Reference   Reference  
 Retreatment cases 445 (67.6) 298 (80.8) 104 (84.6) 214 (25.9) 5.992 (4.763,7.538) < 0.001 5.958 (4.738,7.492) < 0.001 12.777 (9.356,17.448) < 0.001 12.753 (9.349,17.397) < 0.001 16.778 (9.959,28.268) < 0.001 16.498 (9.816,27.728) < 0.001
Contact history
 No 565 (85.9) 317 (85.9) 108 (87.8) 748 (90.6) Reference   Reference   Reference     Reference    
 Yes 93 (14.1) 52 (14.1) 15 (12.2) 78 (9.4) 1.408 (0.985,2.014) 0.060 1.428 (1.000,2.039) 0.050 1.247 (0.794,1.960) 0.338    1.049 (0.532,2.069) 0.889   
  1. Note: * indicates that the difference is statistically significant compared with 2014
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BMC Microbiology

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