Skip to main content
Fig. 5 | BMC Microbiology

Fig. 5

From: Chitin-rich heteroglycan from Sporothrix schenckii sensu stricto potentiates fungal clearance in a mouse model of sporotrichosis and promotes macrophages phagocytosis

Fig. 5

Heteroglycan stimulated cytokine secretion at different time points. A TNF-α expression was significantly upregulated at 24 h and 48 h upon heteroglycan treatment compared to that of the untreated cells. *, p < 0.05. B IL-12 expression was significantly upregulated with conidial stimulation at 24 h compared to that after heteroglycan stimulation. *, p < 0.05. However, IL-12 expression gradually increased within 72 h with heteroglycan treatment compared to the control. C IL-10 expression increased significantly with conidial stimulation at 24 h compared to heteroglycan stimulation. *, p < 0.05. The data were from a representative experiment performed in triplicate

Back to article page

BMC Microbiology

ISSN: 1471-2180

Contact us