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Fig. 4 | BMC Microbiology

Fig. 4

From: Chitin-rich heteroglycan from Sporothrix schenckii sensu stricto potentiates fungal clearance in a mouse model of sporotrichosis and promotes macrophages phagocytosis

Fig. 4

Conidial phagocytosis by macrophages from uninfected mice after incubation for 48 h. Conidia and cigar-shaped yeast forms of S. schenckii s str (black arrow) were observed in the macrophages. However, the percentage of phagocytosing cells and the mean number of ingested fungi in macrophages were lower in the untreated group (A) than in the heteroglycan-treated group (B). Scale bar, 50 μm. The phagocytic index of macrophages was higher in the heteroglycan-treated group than in the untreated group (C). ***, p < 0.001. The data of phagocytosis assay were performed in triplicate

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