Skip to main content
Fig. 3 | BMC Microbiology

Fig. 3

From: Chitin-rich heteroglycan from Sporothrix schenckii sensu stricto potentiates fungal clearance in a mouse model of sporotrichosis and promotes macrophages phagocytosis

Fig. 3

Histopathologic analysis by H&E and PAS staining in infected mice after 5 weeks. A represents the heteroglycan-treated group (n = 10). A1 exhibited reduced granulomatous inflammation with a few mononuclear cells, epithelioid cells, and lymphocyte infiltration in the dermal tissue, as assessed by H&E staining; A2 showed that fungi were rarely observed in the lesion, as assessed by PAS staining. B represents the untreated group (n = 10). B1 exhibited suppurative granulomatous inflammation with numerous neutrophils, mononuclear cells, and lymphocytes in the outer layer of the lesions, as assessed by H&E staining; B2 showed that round, oval and cigar-shaped yeast forms of S. schenckii s str (black arrow) were observed in the lesion, as assessed by PAS staining. Scale bar, 50 μm

Back to article page

BMC Microbiology

ISSN: 1471-2180

Contact us