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Fig. 2 | BMC Microbiology

Fig. 2

From: Chitin-rich heteroglycan from Sporothrix schenckii sensu stricto potentiates fungal clearance in a mouse model of sporotrichosis and promotes macrophages phagocytosis

Fig. 2

The nodule sizes were monitored weekly in infected mice for 5 weeks (n = 20). (a) The nodule sizes of the infected mice with heteroglycan treatment (n = 10) decreased significantly compared to those of untreated mice (n = 10) at the end of the 4th and 5th weeks. *, p < 0.05. (b) Lesions in the untreated group (A, black arrow) were worse compared to those in the heteroglycan-treated group (B, black arrow) at the end of the 5th week. Yellow pus was extruded from the lesions of the untreated group (C, black arrow), whereas no pus extrusion was observed in the heteroglycan-treated group (D) at the end of the 5th week. (c) There were more fungal colonies from lesions in the untreated group than in the heteroglycan-treated group at the end of the 5th week. ***, p < 0.001

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BMC Microbiology

ISSN: 1471-2180

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