Table 3 Antibiotic resistance gene profiles and antimicrobial resistance profiling in PMQR-positive and PMQR-negative isolates
Antimicrobial resistance profiling | CRKPs (n = 149) | P-values | ||||
|---|---|---|---|---|---|---|
PMQR+ (n = 89) | % | PMQR− (n = 60) | % | |||
Carbapenem resistance genes | blaNDM | 26 | 29.2 | 3 | 5 | < 0.01 |
blaKPC | 51 | 57.3 | 48 | 80 | < 0.01 | |
blaIMP | 0 | 0 | 3 | 5 | > 0.05 | |
blaNDM + blaKPC | 9 | 10.1 | 5 | 8.3 | > 0.05 | |
blaIMP + blaKPC | 1 | 1.1 | 0 | 0 | 1 | |
ESBL genes | blaCTX-M | 41 | 46.1 | 31 | 51.7 | > 0.05 |
blaSHV | 5 | 5.6 | 5 | 8.3 | > 0.05 | |
blaCTX-M + blaSHV | 26 | 29.2 | 21 | 35 | > 0.05 | |
Antimicrobial | Imipenem | 88 | 98.9 | 58 | 96.7 | > 0.05 |
Meropenem | 89 | 100.0 | 60 | 100 | > 0.05 | |
Cefoxitin | 86 | 96.6 | 58 | 96.7 | > 0.05 | |
Cefotaxime | 88 | 98.9 | 60 | 100 | > 0.05 | |
Cefepime | 88 | 98.9 | 59 | 98.3 | > 0.05 | |
Ceftazidime | 87 | 97.8 | 59 | 98.3 | > 0.05 | |
Aztreonam | 79 | 88.8 | 58 | 96.7 | > 0.05 | |
Gentamicin | 52 | 58.4 | 45 | 75.0 | < 0.05 | |
Amikacin | 35 | 39.3 | 40 | 66.7 | < 0.01 | |
Ceftazidime/ avibactam | 28 | 31.5 | 9 | 15.0 | < 0.05 | |
Polymyxin B | 2 | 2.2 | 3 | 5.0 | > 0.05 | |
Tigecycline | 4 | 4.5 | 0 | 0 | > 0.05 | |
Piperacillin/ tazobactam | 80 | 89.9 | 54 | 90.0 | > 0.05 | |
Ciprofloxacin | 65 | 73.0 | 52 | 86.7 | < 0.05 | |
Tetracycline | 68 | 76.4 | 12 | 20.0 | < 0.01 | |
Minocycline | 52 | 58.4 | 12 | 20.0 | < 0.01 | |
Sulfamethoxazole | 65 | 73.0 | 17 | 28.3 | < 0.01 | |