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Table 4 Distribution of clusters with greater that four cases in South Africa by provinces (2014–2018)

From: Distribution and Clonality of drug-resistant tuberculosis in South Africa

Family

SIT

24-loci MIRU-VNTR cluster

Cluster size

WC

Number of cases per province

NC

NW

EC

FS

GP

KZN

MP

Beijing

1

234,233,352,844,425,173,453,823

270

262

1

 

2

2

3

  

235,213,342,844,425,163,353,933

113

 

100

2

 

3

2

 

6

244,232,352,644,425,173,354,624

65

 

60

  

2

2

1

 

235,213,342,644,425,163,353,933

55

 

45

4

2

1

1

1

1

244,232,352,644,425,173,354,624

44

44

       

235,213,342,834,425,163,353,933

21

 

14

1

  

3

1

2

244,233,352,242,425,173,353,824

17

17

       

244,232,352,644,425,174,354,624

16

 

16

      

234,233,352,444,425,173,453,823

15

 

1

 

2

4

8

  

244,232,352,644,425,174,356,624

14

 

13

   

1

  

244,232,352,644,425,193,356,622

  

7

 

1

3

1

 

2

244,233,352,844,425,183,353,823

12

12

       

235,213,342,644,425,163,353,933

 

12

       

244,232,352,644,425,174,354,624

11

11

       

2,352,133,426(8)44425163353933

10

 

9

1

     

235,213,342,744,425,163,353,933

  

7

1

1

 

1

  

244,232,352,544,425,174,354,624

9

 

4

  

2

 

3

 

244,233,352,844,425,183,356,223

  

7

1

   

1

 

234,233,352,444,425,173,453,223

8

 

1

 

1

6

   

244,232,352,444,425,173,354,624

7

 

7

      

244,232,352,644,425,173,354,224

  

3

  

1

 

2

1

244,233,352,644,425,183,353,823

  

4

 

2

   

1

245,233,252,844,425,173,356,823

  

1

 

3

 

2

 

1

235,213,342,834,425,123,353,933

 

7

       

244,233,352,644,425,182,353,823

 

7

       

244,232,352,644,425,172,354,624

6

6

       

235,213,342,644,425,163,353,133

  

5

   

1

  

244,213,352,444,425,171,353,823

    

2

 

3

 

1

244,233,352,544,425,174,353,823

    

1

2

1

1

1

244,233,352,844,425,174,356,823

  

1

   

3

 

2

244,232,352,644,425,193,354,622

5

 

4

 

1

    

244,233,352,544,425,173,346,823

  

5

      

244,233,352,544,425,174,356,823

     

1

1

1

2

244,233,352,844,425,183,353,223

  

5

      

235,113,342,644,425,163,353,832

 

5

       

2,352,133,426,444,251,633,531,133

 

5

       

244,033,352,544,425,173,353,823

 

5

       

244,223,352,644,425,183,353,823

 

5

       

244,232,352,544,425,173,354,624

 

5

       

244,233,352,544,425,174,353,823

 

5

       

244,233,352,544,425,183,353,823

 

5

       

EAI1_SOM

48

2,225,342,112,393,246,223,347,211

48

 

1

 

4

 

43

  

222,534,242,393,246,223,347,211

17

 

2

   

12

 

3

2,225,342,112,393,246,223,346,211

6

 

1

   

5

  

2,225,342,112,393,246,223,347,111

5

 

1

   

3

 

1

LAM4

60

134,244,332,224,126,153,332,832

31

 

2

 

9

13

2

3

1

134,244,332,224,126,153,332,232

13

 

3

  

5

2

1

2

LAM3

33

243,234,342,324,226,153,131,722

15

10

1

     

4

244,234,342,424,226,153,136,722

7

 

1

3

 

1

 

1

1

244,234,342,424,226,153,131,722

5

 

2

    

1

2

X1

119

243,224,332,334,425,153,333,732

28

28

       

X3

92

243,244,332,234,425,153,334,932

15

 

2

  

4

9

  

243,244,332,334,425,153,334,832

13

 

4

1

2

 

2

1

3

253,254,332,333,425,153,323,832

8

8

       

243,244,332,334,425,153,224,832

6

       

6

243,247,432,334,424,153,335,832

5

     

5

  

H3

50

223,245,432,234,425,183,333,732

10

 

2

 

2

2

4

  

H

N/A

123,233,332,834,425,153,333,632

11

    

1

1

1

8

T1

53

224,243,122,334,215,153,335,222

8

 

4

   

2

 

2

719

244,234,342,424,226,153,136,222

7

 

2

    

1

4

53

224,243,122,234,225,153,331,422

6

 

4

 

2

    

S

 

324,343,212,324,225,143,336,222

8

 

1

 

1

4

2

  

324,343,212,824,225,143,336,222

6

 

1

  

3

1

 

1

Unknown genotype

N/A

243,244,332,334,425,153,334,832

5

5

       
  1. SIT Shared International Type, WC Western Cape, EC Eastern Cape, FS Free State, GP, Gauteng, KZN KwaZulu-Natal, MP Mpumalanga, NC Northern Cape, NW North West