Fig. 5

a Correlation between stool physiological parameters and the bacterial group abundances. Heat map showing the Spearman’s correlation coefficients between stool physiological parameters and the bacterial group abundances (Family level, 16S rRNA data) from day 3 till week 22. The Spearman’s rank correlation coefficients were determined by combining the biological datasets from all 4 groups. b Correlation between stool physiological parameters and the functional bacterial group abundances (strict and facultative anaerobes). Heat map showing the Spearman’s correlation coefficients between stool physiological parameters and the functional group abundances (strict and facultative anaerobes, 16S rRNA data) from day 3 till week 22. The Spearman’s rank correlation coefficients were determined by combining the biological datasets from all 4 groups. c Correlation between stool physiological parameters and the functional bacterial group abundances (Lactic acid bacteria determined with The Bergey’s Manual of Systematics of Archaea and Bacteria, supplementary Table S10). Heat map showing the Spearman’s correlation coefficients between physiological parameters and the functional group abundances (Lactic Acid Bacteria(LAB), 16S rRNA data) from day 3 till week 22. The Spearman’s rank correlation coefficients were determined by combining the biological datasets from all 4 groups. d Correlations between Bifidobacterium breve/Klebsiella at metagenomics and metatranscriptomics levels. Bar plots depicting correlations between Bifidobacterium breve/Klebsiella and functional genes (DNA and mRNA, SEED data)