Fig. 4

a Relative abundance of strict anaerobes and facultative anaerobes/aerobes. Line plots of the relative abundance of strict anaerobes and facultative anaerobes/aerobes from day 3 till week 22. Non-parametric Mann-Whitney U tests, P < 0.05, P < 0.01 and P < 0.001 are indicated by (Synbiotic vs Control: *, **, ***), (Synbiotic vs Prebiotic: +, ++, +++), (Synbiotic vs Reference, Vaginal Birth: ^, ^^, ^^^), (Reference, Vaginal Birth vs Control: ~, ~~, ~ ~ ~) respectively. b Relative abundance of strict anaerobes. Stacked bar plots of the relative abundance of the key bacterial groups at the Family level that contribute to the strict anaerobes from day 3 till week 22. c Relative abundance of the facultative anaerobes/aerobes. Stacked bar plots of the relative abundance of the key bacterial groups at the Family level that contribute to the facultative anaerobes/aerobes from day 3 till week 22