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Fig. 1 | BMC Microbiology

Fig. 1

From: A synbiotic intervention modulates meta-omics signatures of gut redox potential and acidity in elective caesarean born infants

Fig. 1

Infographic depicting the study design. Depiction of the multi-omics approach used to investigate the functional impact of mode of delivery and nutritional interventions on the infant gut microbiome. In this study, the infants were mixed fed. Subjects from each group of infants born by elective C-section (Synbiotic, Prebiotics and Control) received the study product corresponding to their allocated group in addition to breastfeeding. The group of vaginally born infants or Reference group was also mixed fed and a control formula was provided. This allowed us to ascertain that observed differences between study arms and the reference group resulted from mode of delivery and nutritional interventions. In this study, the number of subjects per group whose faecal genomic DNA was available for 16S rRNA sequencing, was as follows: Synbiotic group (n = 44), Prebiotic group (n = 39), Control group (n = 44) and Reference group (n = 26) and those numbers are reflected in Figure 1

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