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Table 5 WhiB7 regulon genes upregulated in M. chelonae double lysogens relative to the WT M. chelonae (McProf)

From: Increased whiB7 expression and antibiotic resistance in Mycobacterium chelonae carrying two prophages

MCHa gene ID

Predicted function

log2 FCb

FDRc

MABd gene ID

Predicted Function

BB28_RS19005

hypothetical protein

6.1

9.1E-18

MAB_3786c

Hypothetical protein

BB28_RS23100

N-acetyltransferase

5.6

4.4E-38

MAB_4621c

Putative acetyltransferase

BB28_RS23095

hypothetical protein

5.2

2.8E-35

MAB_4620c

Hypothetical protein

BB28_RS17590

WhiB7 transcriptional regulator

4.7

1.3E-73

MAB_3508c

Putative transcriptional regulator

BB28_RS05390

GNAT family N-acetyltransferase (eis1)

4.1

5.8E-12

MAB_1125c

Hypothetical acetyltransferase, GNAT family

BB28_RS06460

NAD(P)-dependent oxidoreductase

3.4

1.2E-21

MAB_1344c

Putative DTDP-glucose-4,6-dehydratase-related protein

BB28_RS11540

ABC transporter ATP-binding protein

3.3

3.5E-64

MAB_2355c

Putative ABC transporter ATP-binding protein

BB28_RS22650

GNAT family N-acetyltransferase (eis2)

3.3

1E-176

MAB_4532c

N- acetyltransferase( eis2)

BB28_RS06750

tap multidrig efflux transporter

3.3

7.3E-35

MAB_1409c

Putative drug antiporter protein precursor

BB28_RS13560

TetV Efflux Pump

3.3

9.8E-94

MAB_2780c

TetV Efflux Pump

BB28_RS20470

pyridoxamine 5'-phosphate oxidase family protein

3.2

4.0E-29

MAB_4054c

Hypothetical protein

BB28_RS17050

hypothetical protein

3.2

5.1E-32

MAB_3424c

hypothetical protein

BB28_RS01940

N-acetyltransferase

3.0

2.9E-11

MAB_0404c

Putative acetyltransferase

BB28_RS09285

ABC transporter ATP-binding protein

2.9

2.7E-07

MAB_1846

Putative ABC transporter ATP-binding protein

BB28_RS12530

18 kDa antigen (HSP 16.7)

2.3

2.5E-31

MAB_3467c

18 kDa antigen (HSP 16.7)

BB28_RS03635

EamA/RhaT family transporter

2.0

1.4E-04

MAB_0766

Hypothetical conserved integral membrane protein

BB28_RS18890

membrane protein

1.8

1.9E-17

MAB_3762

hypothetical protein

BB28_RS17595

hypothetical protein

1.8

3.6E-41

MAB_3509c

Hypothetical protein

BB28_RS06440

TIGR00730 family Rossman fold protein

1.6

2.7E-08

MAB_1340

hypothetical protein

BB28_RS13900

methyltransferase domain-containing protein

1.6

1.6E-13

MAB_2845

Probable trans-aconitate methyltransferase

BB28_RS05350

hypothetical protein

1.6

2.2E-27

MAB_1117c

Hypothetical protein

BB28_RS14985

GTPase HflX

1.5

8.4E-33

MAB_3042c

Probable GTP-binding protein HflX

BB28_RS20665

isocitrate lyase (AceA)

1.5

3.9E-12

MAB_4095c

Isocitrate lyase (AceA)

BB28_RS06230

hypothetical protein

1.5

2.7E-03

MAB_1296

hypothetical protein

BB28_RS06840

hypothetical protein

1.5

1.1E-05

MAB_1413

hypothetical protein

BB28_RS00915

cation transporter

1.5

4.6E-29

MAB_0183c

Putative cation transporter

BB28_RS19745

LysE family translocator

1.5

3.7E-07

MAB_3913

Putative translocator

BB28_RS06445

TIGR00730 family Rossman fold protein

1.4

2.1E-06

MAB_1341

hypothetical protein

BB28_RS12685

aminoglycoside phosphotransferase

1.1

1.6E-02

MAB_4837c

Possible phosphotransferase

BB28_RS14560

GNAT family N-acetyltransferase

1.0

2.7E-17

MAB_2959

Putative acetyltransferase

  1. aMCH = Mycobacterium chlelonae
  2. bLog2 Fold Change for the double lysogen (+BPs+McProf) of M. chelonae
  3. cFDR = False Discovery Rate
  4. dMAB = Mycobacterium abscessus