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Table 1 Minimum inhibitory concentrations of antibacterial agents against bacteria and emm genotype in S. pyogenes

From: Effectiveness of antibacterial agents against cell-invading bacteria such as Streptococcus pyogenes and Haemophilus influenzae

A
strain MIC (μg/ml)
GRNX LVFX CAM AMPC CDTR-PI
NTHi 1 0.06 0.06 4 0.5 0.06
NTHi 2 0.06 0.06 4 0.5 0.06
NTHi 3 0.06 0.06 8 0.5 0.06
NTHi 4 0.06 0.06 2 0.5 0.06
NTHi 5 0.06 0.06 4 0.5 0.06
B
strain emm genotype MIC (μg/ml)
GRNX LVFX CAM AMPC CDTR-PI
S. pyogenes 1 emm 89 0.06 0.5 0.25 0.06 0.06
S. pyogenes 2 emm 75 0.06 0.5 16 0.06 0.06
S. pyogenes 3 emm 11 0.12 2 0.25 0.06 0.06
S. pyogenes 4 emm 28 0.12 0.5 0.25 0.06 0.06
  1. Genotyping of the emm gene encoding the M protein was performed according to the protocol presented by the Center for Disease Control and Prevention
  2. MIC minimum inhibitory concentration, NTHi nontypeable Haemophilus influenzae, S. pyogenes Streptococcus pyogenes, GRNX garenoxacin, LVFX levofloxacin, CAM clarithromycin, AMPC amoxicillin, CDTR-PI cefditoren pivoxil