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Table 2 Solvent used in preparation of antibiotics and concentrations used in assays

From: A high-throughput screening assay based on automated microscopy for monitoring antibiotic susceptibility of Mycobacterium tuberculosis phenotypes

Antibiotic

Solvent

Dose response

ranges (µg/ml)

Checkerboard assaya (µg/ml)

Rifampicin

DMSO

10–1 × 10− 6

1

Isoniazid

H2O

10–1 × 10− 5

0.1

Linezolid

DMSO

10–0.01

1

Levofloxacin

DMSO

10–0.01

1

Ethambutol

DMSO

40–0.04

4

Clofazimine

DMSO

10–0.001

10

Moxifloxacin

H2O

10–0.01

0.25

Pretomanid

DMSO

10–0.01

1

  1. asubinhibitory concentrations