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Fig. 7 | BMC Microbiology

Fig. 7

From: A high-throughput screening assay based on automated microscopy for monitoring antibiotic susceptibility of Mycobacterium tuberculosis phenotypes

Fig. 7

Comparison of differences in IC50 and MIC values for all antibiotics. IC50 and MIC values were compared between planktonic and cording phenotypes for each individual antibiotic (a and c) and all antibiotics combined (b and d). Data is presented as concentration (µg/ml) ± CI (95 %) determined by nonlinear regression for IC50 and Gompertz function for MIC (n = 3). Significant difference between planktonic and cording phenotype is indicated with *(p ≤ 0.05) and non-significant difference with ns as determined by paired, two-tailed t-test. Isoniazid (black), rifampicin (red), linezolid (green), levofloxacin (blue), ethambutol (white), clofazimine (orange), moxifloxacin (violet) and pretomanid (yellow). Graphs were made by GraphPad Prism 9, version 9.0.0 (https://www.graphpad.com)

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