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Table 5 Univariate and multivariate regression analysis showing the socio-demographic, behavioral and clinical factors associated with multidrug-resistant TB in patients with PTB and EPTB

From: Diagnostic utility of GeneXpert MTB/RIF assay versus conventional methods for diagnosis of pulmonary and extra-pulmonary tuberculosis

Variables Patients infected with rifampicin- resistant strains (n = 27) Patients infected with rifampicin- susceptible strains (n = 124) P-value
Age (years)    U
 Mean ±SD 49.44±14.88 48.72±14.81 0.82
 Range 15 – 77 15 – 77
Age groups
 0 – 15 1 (33.3) 2 (66.7) 0.73
 16 – 35 6 (13.3) 39 (86.7)
 36 – 60 15 (19.5) 62 (70.5)
 >60 5 (19.2) 21 (80.8)
Gender
 Male 23 (19.0) 98 (81.0) 0.47
 Female 4 (13.3) 26 (86.7)
Residence    FE
 Rural 26 (21.0) 98 (79.0) 0.049
 Urban 1 (3.7) 26 (96.3)
Smoking
 Positive 19 (22.4) 66 (77.6) 0.10
 Negative 8 (12.1) 58 (87.9)
TB type
 ▪ PTB 14 (12.6) 97 (87.4) 0.005*
 ▪ EPTB 13 (32.5) 27 (67.5)
Positive Smear
 ▪ Yes 14 (13.2) 92 (86.8) 0.02*
 ▪ No 13 (28.9) 32 (71.1)
Previous TB treatment    FE
 ▪ Yes 20 (19.4) 114 (80.6) 0.02*
 ▪ No 7 (41.2) 10 (58.8)  
Contact with a known TB Patient
 ▪ Yes 18 (24.7) 55 (75.3) 0.035*
 ▪ No 9 (11.5) 69 (88.5)  
HIV results
 Unknown 11 (15.9) 58 (84.1) 0.39
 Positive 2 (40.0) 3 (60.0)
 Negative 13 (17.1) 63 (82.8)
Residence 1.95 1.07 0.07 2.110.07 1.11 – 3.15
  Multivariate regression analysis
  B SE P Value Odds ratio 95% CI
TB type 1.41 0.49 0.004 4.21 2.15 – 5.48
Smear 0.10 0.48 0.83 0.91 0.56 – 1.22
Contact with TB case 1.05 0.49 0.03 2.85 1.19 – 7.88
  1. U Mann Whitney U, FE Fisher's Exact test, *Significant statistical difference