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Table 5 Univariate and multivariate regression analysis showing the socio-demographic, behavioral and clinical factors associated with multidrug-resistant TB in patients with PTB and EPTB

From: Diagnostic utility of GeneXpert MTB/RIF assay versus conventional methods for diagnosis of pulmonary and extra-pulmonary tuberculosis

Variables

Patients infected with rifampicin- resistant strains (n = 27)

Patients infected with rifampicin- susceptible strains (n = 124)

P-value

Age (years)

  

U

 Mean ±SD

49.44±14.88

48.72±14.81

0.82

 Range

15 – 77

15 – 77

Age groups

 0 – 15

1 (33.3)

2 (66.7)

0.73

 16 – 35

6 (13.3)

39 (86.7)

 36 – 60

15 (19.5)

62 (70.5)

 >60

5 (19.2)

21 (80.8)

Gender

 Male

23 (19.0)

98 (81.0)

0.47

 Female

4 (13.3)

26 (86.7)

Residence

  

FE

 Rural

26 (21.0)

98 (79.0)

0.049

 Urban

1 (3.7)

26 (96.3)

Smoking

 Positive

19 (22.4)

66 (77.6)

0.10

 Negative

8 (12.1)

58 (87.9)

TB type

 ▪ PTB

14 (12.6)

97 (87.4)

0.005*

 ▪ EPTB

13 (32.5)

27 (67.5)

Positive Smear

 ▪ Yes

14 (13.2)

92 (86.8)

0.02*

 ▪ No

13 (28.9)

32 (71.1)

Previous TB treatment

  

FE

 ▪ Yes

20 (19.4)

114 (80.6)

0.02*

 ▪ No

7 (41.2)

10 (58.8)

 

Contact with a known TB Patient

 ▪ Yes

18 (24.7)

55 (75.3)

0.035*

 ▪ No

9 (11.5)

69 (88.5)

 

HIV results

 Unknown

11 (15.9)

58 (84.1)

0.39

 Positive

2 (40.0)

3 (60.0)

 Negative

13 (17.1)

63 (82.8)

Residence

1.95

1.07

0.07

2.110.07

1.11 – 3.15

 

Multivariate regression analysis

 

B

SE

P Value

Odds ratio

95% CI

TB type

1.41

0.49

0.004

4.21

2.15 – 5.48

Smear

0.10

0.48

0.83

0.91

0.56 – 1.22

Contact with TB case

1.05

0.49

0.03

2.85

1.19 – 7.88

  1. U Mann Whitney U, FE Fisher's Exact test, *Significant statistical difference