Table 1 Identification of potential biomarkers of H-HF
No | Retention time(s) | Metabolite identification | Molecular formula | Ion form | MZ | KEGG ID |
|---|---|---|---|---|---|---|
1 | 230.706 | Pyruvic acid | C3H4O3 | ES− | 87.00772076 | C00022 |
2 | 77.84335 | Uracil | C4H4N2O2 | ES− | 111.01899 | C00106 |
3 | 282.828 | L-Norleucine | C6H13NO2 | ES− | 130.0863208 | C01933 |
4 | 66.92525 | Lithocholic acid | C24H40O3 | ES− | 375.2900014 | C03990 |
5 | 210.881 | Cholic acid | C24H40O5 | ES− | 407.280768 | C00695 |
6 | 189.278 | Hypoxanthine | C5H4N4O | ES+ | 137.0456494 | C00262 |
7 | 324.4045 | L-Proline | C5H9NO2 | ES− | 114.0550451 | C00148 |
8 | 48.528 | Capric acid | C10H20O2 | ES− | 171.1384219 | C01571 |
9 | 314.297 | L-Valine | C5H11NO2 | ES+ | 118.0862667 | C00183 |
10 | 288.356 | Choline | C5H14NO | ES+ | 104.1071126 | C00114 |
11 | 336.777 | gamma-Aminobutyric acid | C4H9NO2 | ES− | 102.0550772 | C00334 |
12 | 46.0601 | Harman | C12H10N2 | ES+ | 183.091462 | C09209 |
13 | 190.9455 | Creatinine | C4H7N3O | ES+ | 114.0663089 | C00791 |
14 | 402.345 | D-Maltose | C12H22O11 | ES+ | 365.1042254 | C00208 |
15 | 47.4337 | Undecanoic acid | C11H22O2 | ES− | 185.1540159 | C17715 |
16 | 359.129 | L-Alanine | C3H7NO2 | ES+ | 90.05519587 | C00041 |
17 | 398.0985 | Glutaric acid | C5H8O4 | ES− | 131.034148 | C00489 |
18 | 326.4825 | 15-Keto-prostaglandin E2 | C20H30O5 | ES− | 349.2016798 | C04707 |
19 | 223.7705 | Oleamide | C18H35NO | ES+ | 282.2778295 | C19670 |
20 | 234.303 | Tetradecanedioic acid | C15H24NO4PS | ES− | 257.1754713 | C11002 |
21 | 302.881 | Urocanic acid | C6H6N2O2 | ES+ | 139.0499338 | C00785 |
22 | 394.914 | Niacinamide | C6H6N2O | ES+ | 123.0551588 | C00153 |
23 | 281.996 | Dimethylethanolamine | C9H16NO8PR2 | ES+ | 90.09161492 | C04308 |
24 | 255.7855 | (13E)-11a-Hydroxy-9,15-dioxoprost-13-enoic acid | C20H32O5 | ES− | 351.2172613 | C04654 |
25 | 358.403 | 4-Hydroxyproline | C5H9NO3 | ES− | 130.0500239 | C01157 |
26 | 298.929 | Trimethylamine N-oxide | C3H9NO | ES+ | 76.07608207 | C01104 |
27 | 334.166 | Betaine | C5H11NO2 | ES− | 116.0707807 | C00719 |
28 | 286.6195 | Norvaline | C5H11NO2 | ES+ | 118.0862646 | C01799 |
29 | 43.08045 | Palmitoleic acid | C16H30O2 | ES− | 253.2168827 | C08362 |
30 | 311.8905 | Pyroglutamic acid | C5H7NO3 | ES− | 128.0344652 | C01879 |
31 | 212.083 | Prostaglandin E3 | C20H30O5 | ES− | 349.2017343 | C06439 |
32 | 332.553 | D-Alanyl-D-alanine | C6H12N2O3 | ES− | 159.0767659 | C00993 |
33 | 419.462 | Histamine | C5H9N3 | ES+ | 112.0869868 | C00388 |
34 | 174.24 | PE(15:0/14:0) | C7H12NO8PR2 | ES+ | 650.4736181 | C00350 |
35 | 333.989 | Imidazoleacetic acid | C5H6N2O2 | ES+ | 127.050143 | C02835 |