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Fig. 4 | BMC Microbiology

Fig. 4

From: Lactobacillus rhamnosus HDB1258 modulates gut microbiota-mediated immune response in mice with or without lipopolysaccharide-induced systemic inflammation

Fig. 4

Effect of HDB1258 and SC β-glucan on the gut microbiota composition in mice. A Effects on α-diversity (OUT richness). B Effects on β-diversity. C Effects on the gut bacteria composition at the phylum level. D The correlation between gut microbiota (at the family and genus levels) and ratio of TNF-α to IL-10 expression in the colon. E The correlation between gut microbiota (at the family and genus levels) and TNF-α to IL-10 expression ratio in the spleen. HDB1258 (LL, 1 × 108 CFU/mouse/day and LH, 1 × 109 CFU/mouse/day) or SC β-glucan (SCG, 50 mg/kg/day) was orally gavaged daily for 14 days. Normal control group (NC) was treated with saline instead of test agents. Cytokine expression levels in the spleen were assayed using qPCR and those in the colon were using ELISA. Data values were described as mean ± SD (n = 7). #p < 0.05 vs. NC

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BMC Microbiology

ISSN: 1471-2180

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