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Table 1 Antimicrobial susceptibility testing of 72 invasive and colonizing GBS

From: Prevalence, population structure, distribution of serotypes, pilus islands and resistance genes among erythromycin-resistant colonizing and invasive Streptococcus agalactiae isolates recovered from pregnant and non-pregnant women in Isfahan, Iran

 

Colonizing n (%)

Invasive n (%)

Antibiotic

Susceptible

Intermediate

Resistant

Susceptible

Intermediate

Resistant

Penicillin

36 (100)

–

–

36 (100)

–

–

Cefepime

36 (100)

–

–

36 (100)

–

–

Ceftriaxone

36 (100)

–

–

36 (100)

–

–

Cefotaxime

36 (100)

–

–

36 (100)

–

–

Vancomycin

36 (100)

–

–

36 (100)

–

–

Tetracycline

2 (5.5)

–

34 (94.4)

5 (13.8)

–

31 (86.1)

Levofloxacin

29 (80.5)

5 (13.8)

2 (5.5)

27 (75%)

4 (11.1)

5 (13.8)

Clindamycin

14 (38.8)

11 (30.5)

11 (30.5)

19 (52.7)

6 (16.6)

11 (30.5)

Erythromycin

10 (27.7)

11 (30.5)

15 (41.6)

17 (47.2)

4 (11.1)

15 (41.6)

iMLSBa

5 (13.8)

4 (11.1)

c MLSB b

9 (25)

9 (25)

M phenotype c

1 (2.7)

2 (5.5)

L phenotype d

2 (5.5)

2 (5.5)

MDR

10 (27.7)

6 (16.6)

Total

36

36

  1. a Inducible Macrolides, Lincosamides, and Streptogramin B (MLSB) phenotype with resistance to erythromycin and blunting of zone of inhibition of clindamycin
  2. b Constitutive MLSB with resistance to clindamycin and erythromycin
  3. c Resistant to erythromycin only but not clindamycin by efflux mechanism
  4. d Resistant to clindamycin only without blunting (without D shape)