Fig. 8

TnSeq - Comparison of the essential genes prediction per method. Santiago FE refers to the genes that are identified as fully essential in the Santiago et Al. paper. Santiago AE refers to both fully essential and domain-essential genes. The classification of the regression results has been performed with thresholds of 4 and 12. a Comparison of regression on gene saturation index with the genes identified as essential in Santiago et al. [2]. 255 genes are shared between the regressions and the paper full essential genes list. b Comparison of regression on gene saturation index with the genes identified as non-essential in Santiago et al. The methods do not differ much on non-essential genes predictions. 2071 genes are identified by the paper and the regression, regardless of the chosen threshold. c Comparison of Bio-Tradis prediction of essential genes with the hand-fit regression and paper predictions. 287 genes are common to the three methods, and Bio-Tradis overpredicts 32 genes not identified by other methods. d Comparison of Bio-Tradis prediction of non-essential genes with the hand-fit regression and paper predictions. The results are very similar. 197 genes are predicted by both regressions that are not classified as non-essential by the study. e Comparison of Transit results, regression results, and genes identified as essential in Santiago et al. We are using the hand-fit regression results using a threshold of 4 to be more relaxed, as the threshold of 12 provides more stringent results and Bio-Tradis overpredicts essential genes. f Comparison of Transit results, regression results, and genes identified as non-essential in Santiago et al. The three methods are in accordance with the non-essential genes predictions. 1923 are common across all results